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Showing posts from November, 2011

Poor Glucose Control

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Maria Dalamagka  Poor glycemic control , whether too high or too low, is associated with decreased survival in diabetic patients on hemodialysis, Kamyar Kalantar-Zadeh, MD, MPH, PhD, professor of medicine, pediatrics, and epidemiology at the University of California at Los Angeles David Geffen School of Medicine, reported here at Kidney Week 2011: American Society of Nephrology 44th Annual Meeting. Dr. Kalantar-Zadeh reported that in a 6-year study, moderate hyperglycemia raised the risk for all-cause or cardiovascular mortality of hemodialysis patients with diabetes, and levels of glycated hemoglobin (HbA1c) below 6% or blood glucose below 100 mg/dL were associated with an elevated risk for death. According to most studies, he said, if glucose is well controlled, there are improvements in mortality, microvascular complications, and cardiovascular disease. One study showed that for every 1% decrease in HbA1c, deaths related to diabetes decreased 21%, microvascular complications de...

Child abuse

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Maria Dalamagka Women who suffer either physical or sexual abuse early in life have a significantly increased risk for subsequent cardiovascular events, including myocardial infarction and stroke, a new study suggests. The study, using data from the Nurses' Health Study II, shows that women who reported they had experienced forced sexual activity during childhood or adolescence had a greater than 50% increased risk for cardiovascular disease. The relationship with physical abuse was significant but less robust, the authors note, and will have to be confirmed in other data sets. This is the third study to show that forced sex among girls is linked with at least a 50% increase in cardiovascular event risk, lead author Janet Rich-Edwards, ScD, MPH, associate professor in the Department of Medicine at Brigham and Women's Hospital in Boston, Massachusetts, said at a press conference here. The relationship was only partially explained by traditional cardiovascular risk factors. ...

Autism

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Maria Dalamagka  Autism may be an advantage in some settings and should not be viewed as a defect that needs suppressing, according to a provocative article published online November 2 in Nature. Recent data and my own personal experience suggest it's time to start thinking of autism as an advantage in some spheres, not a cross to bear," said author Laurent Mottron, MD, PhD, from the University of Montreal's Centre for Excellence in Pervasive Development Disorders. According to the article, the definition of autism itself is biased, being characterized by "a suite of negative characteristics," focusing on deficits that include problems with language and social interactions. However, in certain settings, such as scientific research, people with autism exhibit cognitive strength."We think that the kind of strengths and cognitive profile that we find in autistics are much more specific than scientists usually acknowledge," said Dr. Mottron."Unfort...

Fat Melter

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Maria Dalamagka  Deep in the jungles of  West Africa, there are places where obesity is completely unknown. The natives just don’t get fat. A professor doing population studies discovered this curious fact. After watching this group and comparing them to others, he found something unique about their diet: The locals use a paste derived from the seed of a “bush mango” to thicken their soups. This professor, an expert in nutritional biochemistry at the University in nearby Cameroon, created an extract of this seed and ran his own tests. After 10 weeks, the people taking this extract dropped an average of 28 pounds and dropped 6 inches around their waist. The results were published in a national, peer-reviewed medical journal. FOX News picked up the story from Reuters when the study hit the media last year. Along with a healthy diet and regular exercise, you can use this very same natural extract to help drop unwanted fat.

Clot lysis treatment

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Maria Dalamagka  A clot lytic treatment strategy with low-dose recombinant tissue-type plasminogen activator (rtPA) speeds clot removal in patients with intracerebral hemorrhage (ICH) that is complicated by intraventricular hemorrhage (IVH), results of a phase 2 trial confirm. Moreover, it does so with an "acceptable safety profile compared to placebo and historical controls," the authors, led by Neal Naff, MD, from Johns Hopkins University, Baltimore, Maryland, write. One caveat with the novel treatment, however, is that it appears to be associated with more bleeding,said senior author Daniel F. Hanley, MD, also from Johns Hopkins. Still, the aim in treating this condition, which can be almost 100% fatal, is to reduce the patient's exposure to blood, thereby reducing injury to the brain. "This drug has to be used carefully because of the increased risk of bleeding, but it will dissolve the blood clot that has formed in the intraventricular space," Dr. Hanley s...